Clinical Studies

This is an exploratory study to evaluate the safety and effectiveness of concomitant intraarticular (IA) and peri-neural (PN) injections of an investigational veterinary product for the control of elbow pain in dogs. This 28-day study also includes a long term follow up at 3 and 6 months. This study involves a one-time injectable treatment with investigational product under general anesthesia or sedation. This study does include a control group. An estimated 20 client-owned dogs will be enrolled. Owners will be required to report and record abnormal daily observations and complete questionnaires relating to dog’s pain level throughout the study. Study visits include the dog’s initial consultation, treatment Day 0, recheck visits on Day 7, 28, 90, and 180.

Eligibility Criteria:

• In general good health or stabilized for chronic conditions
• ≥1 year of age
• Weight ≥15 kg
• Clinically documented pain originating in at least one elbow and is the only joint on that limb to show signs of pain
• History of persistent lameness due to elbow pain for at least 2 months prior to enrollment
• Any medication used for the treatment of pain has been discontinued at least 10 days prior to screening ü In case of bilateral elbow pain, the most clinically affected joint will be selected
• No elbow pain related to tumors, recent trauma (<2 months), unhealed fractures, immune mediated joint diseases

Participating Hospitals

• Veterinary Specialty Hospital, Sorrento Valley, San Diego, CA